Source: Famous Incest: Six Unbelievable Cases From HistoryCharles Darwin married his first cousin with whom he had ten children. Three died as infants and three were infertile. He was the first to raise the question if incest may cause weaknesses in offspring after studying inbred plants in his garden.
Researchers looked at four generations of Darwin and Wedgwood families and discovered many consanguineous marriages on both sides. As Darwin feared, the similarity between the Wedgwood and Darwin genetic lines contributed to his children’s health issues.