Chronic kidney disease : elevated Creatinine and BUN

[Fluorescent]

@Cerberus

I am sorry to hear about your mother.

Diabetes and Hypertension both take their toll on the kidney. You should get BUN and Creatinine every month.

ACE inhibitors should be started at the first sign of microscopic protein in the urine and it is Renoprotective that is these medicines protect the kidney from excessive filtration injury.

The only side effect you should be looking at are two.

Sometimes ACE inhibitor can cause cough. Just hope it doesn't happen to your mother inshAllah because ideally she needs ACE inhibitors indefinitely.

Also second is they lower potassium levels. I suggest that you do monthly serum electrolytes as well, since your mother is already avoiding potassium diet. Too low potassium can suddenly stop the heart.

Beyond that, feel free to ask any questions. I am certified by the Medical Council of Canada, and can help you extensively in this regard.

My prayers are with you.

ACEIs/ARBs raise K since they antagonize aldosterone (which normally gets rid of K in the collecting duct). CKD itself will cause K retention (due to reduced GFR). This becomes tricky, since you need the ACEIs to slow down further deterioration of renal function, so her electrolytes absolutely need to be watched closely.

Cough / angioedmea won't really be an issue considering she can simply be switched to an ARB.

 

[lifeinabucket]

ACEIs/ARBs raise K since they antagonize aldosterone (which normally gets rid of K in the collecting duct). CKD itself will cause K retention (due to reduced GFR). This becomes tricky, since you need the ACEIs to slow down further deterioration of renal function, so her electrolytes absolutely need to be watched closely.

Cough / angioedmea won't really be an issue considering she can simply be switched to an ARB.

Yes you are right.

I should have said hyperkalemia. For some reason I was tuned into diuretics. Anyways, rest of your post is perfect.

Thanks !

 

[azaabkhan]

Sorry for late response.

Everything is made out of nature. I strongly agree.

But there are unknown number of chemical reactions happening in human body at any given time.

Do you think giving it a dose of concentrated dose of single ciprofloxacin tablet will solve the chained problems?

 

[kamran saeed]

my father was also suffering from same diesease.he remain on dialysis from 2012 to 2016 and couldnt survive more bcz of high bp and diabetes(700+) and a diabtic foot and passed away in may 2016 ,the only advice is that chose the doctor you think best and follow his treatment and dont use treatment of diferent docs for one disease and plz dont try desi totky as in early days when every one is advising that try this this is best the other person did and he become well but whenever we tried it ends up in emergency in hospital

 

[Leon]

my father was also suffering from same diesease.he remain on dialysis from 2012 to 2016 and couldnt survive more bcz of high bp and diabetes(700+) and a diabtic foot and passed away in may 2016 ,the only advice is that chose the doctor you think best and follow his treatment and dont use treatment of diferent docs for one disease and plz dont try desi totky as in early days when every one is advising that try this this is best the other person did and he become well but whenever we tried it ends up in emergency in hospital

I am so sorry to hear this brother.

Sent from my Redmi Note 4 using Tapatalk